20 August 2020

In this episode of the ORS podcast Johnny and the fellas discuss a recent paper that has given additional support to the ability of repeated inflations of a cuff limiting muscle atrophy from disuse. Check out the full podcast here.

We go deeper into how passive application of BFR might affect outcomes in our previous podcast on Cell Swelling.

If you have questions or a topic that you want to hear about, you can submit the topic or question through [email protected] with the subject line #podcast. If your question/topic gets selected, you can receive a free ORS shirt.

Here’s the paper:

Kakehi, S., Tamura, Y., Kubota, A., Takeno, K., Kawaguchi, M., Sakuraba, K., Kawamori, R., & Watada, H. (2020). Effects of blood flow restriction on muscle size and gene expression in muscle during immobilization: A pilot study. Physiological Reports, 8(14), e14516.

Other papers referenced:
Du Bois, P., Pablo Tortola, C., Lodka, D., Kny, M., Schmidt, F., Song, K., Schmidt, S., Bassel-Duby, R., Olson, E. N., & Fielitz, J. (2015). Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression. Circulation Research, 117(5), 424–436.

Joshi, S., Wollenzien, H., Leclerc, E., & Jarajapu, Y. P. (2019). Hypoxic regulation of angiotensin-converting enzyme 2 and Mas receptor in human CD34+ cells. Journal of Cellular Physiology, 234(11), 20420–20431.

Tipton, K. D., Hamilton, D. L., & Gallagher, I. J. (2018). Assessing the Role of Muscle Protein Breakdown in Response to Nutrition and Exercise in Humans. Sports Medicine , 48(Suppl 1), 53–64.

Kubota, A., Sakuraba, K., Koh, S., Ogura, Y., & Tamura, Y. (2011). Blood flow restriction by low compressive force prevents disuse muscular weakness. Journal of Science and Medicine in Sport / Sports Medicine Australia, 14(2), 95–99.

Kubota, A., Sakuraba, K., Sawaki, K., Sumide, T., & Tamura, Y. (2008). Prevention of disuse muscular weakness by restriction of blood flow. Medicine and Science in Sports and Exercise, 40(3), 529–534.

What everyone wanted though…the squirrel story!!

Credit to FoolBoyMedia on free sound.org for the sound byte: